|
Mode of Action (MoA)
|
Binds to the RecC subunit of RecBCD and promotes its recombination activity.
|
|
Evidence
|
Co-purification (ECO_0000022) and electrophoresis showed binding to the RecBCD complex (DOI: 10.1016/S0021-9258(17)31676-9), and genetic interaction evidence (the overexpression of RecC suppresses the phenotype caused by Abc2, ECO_0000011) supports interaction with RecC.
|
|
MoA Category
|
binds and inhibits host defence system
|
|
Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
|
Escherichia coli RecBCD
|
|
Relevant publication(s)
DOI
|
10.1006/jmbi.1999.3486
|
|
Other components of the anti-defence system
Multicomponent System
|
-
|
|
Known structure in PDB
PDB ID
|
-
|
|
Genome(s) encoding the protein
Protein Source
|
Bacteriophage P22
|
|
Defence system(s) inhibited by the protein
Defences
|
RecBCD
|