|
Mode of Action (MoA)
|
None
|
|
Evidence
|
Although not a primary focus, AcrIE9 was included as a comparison. It was expressed from phage and tested on a P. aeruginosa strain with a Type I-E system. The phage formed plaques efficiently (EOP ≈ 1), and CRISPRi rescue confirmed that AcrIE9 blocks Cascade DNA binding.
|
|
MoA Category
|
unknown
|
|
Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
|
Pseudomonas aeruginosa type I-E CRISPR-Cas system
|
|
Relevant publication(s)
DOI
|
10.1093/nar/gkab006
|
|
Other components of the anti-defence system
Multicomponent System
|
-
|
|
Known structure in PDB
PDB ID
|
-
|
|
Genome(s) encoding the protein
Protein Source
|
MGE in Pseudomonas aeruginosa
|
|
Defence system(s) inhibited by the protein
Defences
|
CRISPR-Cas
|