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Mode of Action (MoA)
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None
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Evidence
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In vitro DNA cleavage assays with SpyCas9, SinCas9, SauCas9, and AsCas12a showed strong inhibition of SinCas9, weak inhibition of SpyCas9, SinCas9, and SauCas9 and no inhibition of AsCas12a.
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MoA Category
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unknown
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Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
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Streptococcus pyogenes, Streptococcus aureus, and Streptococcus iniae type II-A CRISPR-Cas
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Relevant publication(s)
DOI
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10.1093/nar/gkaa219
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Other components of the anti-defence system
Multicomponent System
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-
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Known structure in PDB
PDB ID
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-
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Genome(s) encoding the protein
Protein Source
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MGE in Streptococcus agalactiae GB00548
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Defence system(s) inhibited by the protein
Defences
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CRISPR-Cas
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