Bacterial virus anti-defence systems · sequence & structure resource

Encyclopaedia of Bacterial Virus Anti-Defence Systems


Protein: AcrIIC8

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Overview

Mode of Action (MoA) None
Evidence Ectopic expression of AcrIIC8 (ECO_0000017) abolished interference against target plasmid.
MoA Category unknown
Subtype(s) of the defence system(s) inhibited by the protein Defence Subtype Listeria seeligeri type II-C CRISPR-Cas
Relevant publication(s) DOI 10.1038/s41586-024-07923-x
Other components of the anti-defence system Multicomponent System -
Known structure in PDB PDB ID -
Genome(s) encoding the protein Protein Source MGE in Listeria seeligeri
Defence system(s) inhibited by the protein Defences CRISPR-Cas

3D structure

AlphaFold 3 model.

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Feature viewer - predicted secondary structure

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Pfam annotations

No Pfam domains found

Sequence Viewer

Amino acid position: -

MDVTLFLVRALSSQIYEKDINNLFNKHALEAYHEAQSSQFWDSKAIQELPPADEIRARKILGLVCLSVKQEALRDELTTIFFRKIGFVLQRYIVKADTKEYYDTHLEEMKQQINALPQRVLDYVLILLDGNGVEKEQTLNYVYTLLKHWDQEGDIFLGLSEKEKTNTLQLLEEYFPQKKFTSYYDLLKVLYTEKKIDKAHIGAFQYFFISEKISTEEYATQIDIRKAELRQLFAIAVQKELPREIMPFYVISGIESLIVAKSYNKLRNSLLKSDLELVEVKHQVQQNDEVKWKRENALLKQENKRLQERIKFLEGEQHSWNKEEIKTRDETIFILEQLLEKKVNELDQPSNLDMEEEVNTTEEVVLDGLKIAIVGGYPKLNLDLKKEIPDLAIFTTIDRLNKSLQQFDYVFLLTSYSSHAMKMKLDSLKVDYFYLASMTTQSVVKELKKQIQAKAK