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Mode of Action (MoA)
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acts as a Phd-like antitoxin, binding to and inhibiting the Doc toxin (a kinase that targets EF-Tu)
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Evidence
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MoA Category
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binds and inhibits host defence system
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Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
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Sulfolobus islandicus type II TA system PhD-Doc
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Relevant publication(s)
DOI
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10.1038/s41467-024-48074-x
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Other components of the anti-defence system
Multicomponent System
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-
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Known structure in PDB
PDB ID
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-
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Genome(s) encoding the protein
Protein Source
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Sulfolobus islandicus rod-shaped virus
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Defence system(s) inhibited by the protein
Defences
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TA
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