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Mode of Action (MoA)
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depletes the starvation alarmones (p)ppGpp.
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Evidence
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Pyrophosphatase assay measuring ppGpp-degrading activity of Atd1 confirms its function as a nucleotide pyrophosphohydrolase (ECO:0000005).
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MoA Category
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degrades or sequesters molecules utilised by host defence systems
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Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
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TIR response (in vitro)
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Relevant publication(s)
DOI
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10.1016/j.celrep.2023.112305
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Other components of the anti-defence system
Multicomponent System
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-
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Known structure in PDB
PDB ID
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-
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Genome(s) encoding the protein
Protein Source
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Pectobacterium phage PcCB7V
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Defence system(s) inhibited by the protein
Defences
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gp29/gp30
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