Bacterial virus anti-defence systems · sequence & structure resource

Encyclopaedia of Bacterial Virus Anti-Defence Systems


Protein: PsiA

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Overview

Mode of Action (MoA) None
Evidence Deletion (ECO_0007379) or nonsense (ECO_0007161) mutations in the psiB gene abolished SOS inhibition, indicating that PsiB protein is required for the phenotype. Ectopic expression (ECO_0000017) of PsiB alone (12 kDa protein) is sufficient for inhibiting SOS functions.
MoA Category unknown
Subtype(s) of the defence system(s) inhibited by the protein Defence Subtype Escherichia coli SOS response
Relevant publication(s) DOI 10.1093/nar/18.15.4597
Other components of the anti-defence system Multicomponent System -
Known structure in PDB PDB ID -
Genome(s) encoding the protein Protein Source Escherichia coli plasmid
Defence system(s) inhibited by the protein Defences SOS stress response

3D structure

AlphaFold 3 model.

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Feature viewer - predicted secondary structure

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Pfam annotations

Pfam Name Pfam Acc Pfam Length Colour HMM Start HMM End Ali Start Ali End Env Start Env End Evalue
PsiA PF06952 237 4 236 4 235 1 236 1e-40

Sequence Viewer

Amino acid position: -

MSVRSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAFFRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLYAIDVLIETQGEVCLLPLPGDAAERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPETVGSWHARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEASLAAREAGHAVREMERWMVPNKLREAA