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Mode of Action (MoA)
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binds to ThsB (Thoeris type I)
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Evidence
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Ectopic expression (ECO_0000017) of tad6 in Bacillus cereus inhibits Thoeris-mediated antiphage defense in a plaque formation assay. Binding is supported by co-purification in pull-down assays (co-purification evidence, ECO_0006074).
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MoA Category
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binds and inhibits host defence system
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Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
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Bacillus cereus MSX-D12 type I Thoeris
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Relevant publication(s)
DOI
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10.1016/j.cell.2024.12.035
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Other components of the anti-defence system
Multicomponent System
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-
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Known structure in PDB
PDB ID
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-
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Genome(s) encoding the protein
Protein Source
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Ga0105013_100020934 (IMG/VR)
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Defence system(s) inhibited by the protein
Defences
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Thoeris
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