Overview
| Mode of Action (MoA) | None |
| Evidence | Ectopic expression of U56 rescues phage from Retron-Eco1 in plaque assays (ECO_0000017). Purified U56 binds ADPr with micromolar affinity as shown by isothermal titration calorimetry (ECO_0001825). |
| MoA Category | unknown |
| Subtype(s) of the defence system(s) inhibited by the protein Defence Subtype | Escherichia coli type II Retron (Eco1) |
| Relevant publication(s) DOI | 10.1016/j.molcel.2024.05.001 |
| Other components of the anti-defence system Multicomponent System | - |
| Known structure in PDB PDB ID | - |
| Genome(s) encoding the protein Protein Source | Escherichia phage ukendt |
| Defence system(s) inhibited by the protein Defences | Retron |
| View homologs from eukaryotic dsDNA viruses |