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Mode of Action (MoA)
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contains a methyltransferase domain, likely modifying phage.
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Evidence
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Genetic deletions (deletion mutation phenotypic evidence, ECO_0001038) result in high sensitivity to RM systems, while ectopic expression (ECO_0000017) restores plating efficiency.
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MoA Category
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modifies phage molecules to avoid recognition
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Subtype(s) of the defence system(s) inhibited by the protein
Defence Subtype
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Escherichia coli type I RM
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Relevant publication(s)
DOI
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10.1016/0042-6822(87)90324-2,
10.1111/mmi.13705
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Other components of the anti-defence system
Multicomponent System
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dara;
hdf;
ddrb;
ddra;
ulx
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Known structure in PDB
PDB ID
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-
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Genome(s) encoding the protein
Protein Source
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Enterobacteria phage P1
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Defence system(s) inhibited by the protein
Defences
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RM
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View homologs from eukaryotic dsDNA viruses
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